Clinical Research Support

The Clinical Trial begins with a pharmacy consultant. 

Mariner Advanced Pharmacy is a regional provider for decentralized clinical trial solutions with compounding expertise.  The specialty pharmacy strengthens our researchers with provided capabilities such drug sourcing, drug compounding, packaging & dispensing, storage, and controlled primary and secondary engineering control, and equipment & ancillary supplies. Currently, MAPRx hosts a number trials locally, has developed working relationships with many local renowned institutions and is able to source or compound drug products.  The following highlights our capabilities to service small to large trials: 

---

• Procurement, drug design, formulation, packaging to meet protocol specs
• FDA-registered laboratory testing & stability study program.
• USP-Compliant batch production & storage 
• Patient-centric Dispensing. On-call service 24/7. 
• Returns & Destruction 
• Protocol Management & Randomization control
• Shipping/Dispensing with traceability

Active Clinical Trials MAPRx collaborates.

NOTICE: MAPRx does not perform any recruitment.

Stanford University

• The Role of Secondary Bile Acids in Intestinal Inflammation with Ursodiol vs placebo
• Striatal mechanisms and selective target engagement of reward responsiveness in human anhedonia in depression
• Cortical mechanisms and selective target  engagement of reward valuation in human anhedonia in depression
• Pain Relief after Trapeziectomy without Opioids:Ibuprofen & Acetaminophen versus Oxycodone
• Phase I/II Cancer Cell Therapy Dasatinib 0.05mg/ml Soln 15ml Clinical Grade Solution
• Clinical Trial of COVID-19 Convalescent Plasma in Outpatients (C3PO).
• COVID-19 Outpatient Pragmatic Platform Study (COPPS): Acebilustat
• ​Efficacy of Medical Therapy in Women and Men with Angina and Myocardial Bridging
• COVID-19 Outpatient Pragmatic Platform Study (COPPS): Acebilustat
• ​A Phase 2 Randomized, Double Blinded, Placebo Controlled Study of Oral Camostat Mesilate Compared to Standard Supportive Care in Subjects with Mild or Asymptomatic COVID-19
• ​Oral Favipiravir Compared to Placebo in Subjects With Mild COVID-19
• ​Low-dose naltrexone for Bladder Pain Syndrome.
• ​Single-Blind Study of a Single Dose of Peginterferon Lambda-1a Compared With Placebo in Outpatients With Mild COVID-19 (COVID-Lambda)
• ​Intranasal Vasopressin Treatment in Children With Autism
• A Study of Esomeprazole in Children With Autism
• ​A Study of N-Acetyl Cysteine in Children With Autism
• The Effects of Tranexamic Acid on Joint Inflammation and Cartilage Health in Anterior Cruciate Ligament Injured Patients
• NMDAR Modulation As a Therapeutic Target and Probe of Neural Dysfunction in OCD (SU sIRB)
• Ketamine in the Mapping the Influence of Drugs of Abuse on Risk and Reward Circuits
• Opiate Suicide Study in Patients With Major Depression (AFSP)
• Ketamine in OCD NMDAR Modulation as a Therapeutic Target; Probe of Neural Dysfunction in OCD
• Sickness Evaluation at Altitude With Acetazolamide at Relative Dosages (SEAWARD)
• ​The BIomarker Guided Study for Depression (BIG)
• JAK Inhibition to Prevent Ventilator-induced Diaphragm Dysfunction
• Efficacy of Medical Therapy in Women and Men With Angina and Myocardial Bridging
• Postoperative Pain Management in Rhinoplasty: A Randomized Controlled Trial Opiate vs non-opiate
• The Role of Secondary Bile Acids in Intestinal Inflammation
• Feasibility of empagliflozin in managing diuretic-resistant ascites in patients with cirrhosis
• Efficacy of Medical Therapy in Women and Men with Angina and Myocardial Bridging ​

UCSF

• TRIUMPH Trial Is A Prospective, Randomized, Double-Blinded, Parallel-Group, 3-Arm Trial
• Effects of Sleeve Gastrectomy on Calcium Metabolism and the Skeleton
• Metformin for Pulmonary Hypertension HFpEF (PH-HFpEF)
• MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction (MOCHA Trial) (MOCHA)
• Letrozole in Patients With Hepatopulmonary Syndrome
• ​The Effect of NAC on Lung Function and CT Mucus Score (ENACT)
• Effects of Sleeve Gastrectomy on Calcium Metabolism and the Skeleton
• WUBI-Q Protocol, A Double-Blind Randomized Clinical Trial
• Phase II Trial of Metformin for Pulmonary Hypertension in Heart Failure with Preserved Ejection Fraction

UC Berkeley

• Aging Mitochondrial Fragmentation and Metabolic Flexibility Study ,Glucose and Lactate ISOTOPE INFUSION
• Comparison of the effects of dietary folate and phytate on the absorption of zinc from either Zinc-amino acids (ZnAA) or Zinc-chloride (ZnCl2)

Recent Academic Publications

Favipiravir for treatment of outpatients with asymptomatic or uncomplicated COVID-19: a double-blind randomized, placebo-controlled, phase 2 trial. 
Marisa Holubar, MD, Aruna Subramanian, MD, Natasha Purington, PhD, Haley Hedlin, PhD, Bryan Bunning, MS, Katharine S. Walter, PhD, Hector Bonilla, MD, Athanasia Boumis, Michael Chen, MD, Kimberly Clinton,
Liisa Dewhurst, Carol Epstein, MD, Prasanna Jagannathan, MD, Richard H. Kaszynski, MD, Lori Panu, Julie Parsonnet, MD, Elizabeth L. Ponder, PhD, Orlando Quintero, MD, Elizabeth Sefton, PhD, Upinder Singh, MD, Luke Soberanis, Henry Truong, PharmD, Jason R. Andrews, MD, Manisha Desai, PhD, Chaitan Khosla, PhD, Yvonne Maldonado, MD